Adiponectin and leptin levels in HIV-infected patients with lipodystrophy in Southern India
نویسندگان
چکیده
Methods In this cross sectional study, consenting 79 HIV+ve patients on antiretroviral therapy (for more than six months) visiting the Namakkal Government Hospital were recruited. Demography, anthropometry and ART regimens were collected. Patients’ self-perception of lipodystrophy was determined using standardized questionnaires and clinically confirmed. An overnight fasting blood was drawn to determine serum adiponectin (Ray Biotech ELISA), serum leptin (DRG International ELISA) and insulin. Statistical analysis included analysis of variance and Pearson’s correlation.
منابع مشابه
Adipocyte-derived hormone levels in HIV lipodystrophy.
OBJECTIVE Despite evidence for the role of adipocyte-derived hormones in insulin resistance, little is known about their levels in human lipodystrophic states. We examined the relationships of plasma leptin and adiponectin levels to fat distribution and insulin sensitivity in the HIV lipodystrophy syndrome. DESIGN Cross-sectional study SETTING HIV primary care practices PATIENTS HIV-infec...
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BACKGROUND Lipodystrophies are characterized by adipose tissue redistribution, insulin resistance (IR) and metabolic complications. Adipokines and hormones related to body composition may play an important role linking these alterations. Our aim was to evaluate adipocyte-derived hormones (adiponectin, leptin, resistin, TNF-α, PAI-1) and ghrelin plasma levels and their relationship with IR in HI...
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2010